| Date | Time | Opponent | |
|---|---|---|---|
| TBA | 7:00 PM | @ | Pasadena (Pasadena, CA) |
| 9/4/2010 | 7:00 PM | @ | Village Christian (Sun Valley, CA) Location: Glendale High School |
| 9/10/2010 | 7:00 PM | @ | Maranatha (Pasadena, CA) |
| 9/17/2010 | 7:00 PM | vs. | San Marino (San Marino, CA) |
| 9/24/10 | 7:00 PM | vs. | Pasadena (Pasadena, CA) |
| 10/1/2010 | 7:00 PM | vs. | Bosco Tech (Rosemead, CA) * |
| 10/8/2010 | 7:00 PM | @ | St. Bernard (Playa del Rey, CA) * |
| 10/22/2010 | 7:00 PM | vs. | Verbum Dei (Los Angeles, CA) * |
| 10/29/2010 | 7:00 PM | vs. | Mary Star of the Sea (San Pedro, CA) * Location: Daniels Field |
| 11/5/2010 | 7:00 PM | @ | Bishop Montgomery (Torrance, CA) * |
| 11/12/2010 | 7:00 PM | vs. | Cantwell-Sacred Heart (Montebello, CA) * Location: La Salle High School |